Roberto Martinez’s Wigan squad has been reduced to its bare bones with no fewer than eight players sidelined.
Irish midfielder James McCarthy (ankle) is likely to miss the match with an injury sustained against Norwich last week, but Latics are hit hardest at the back with Piscu (hamstring) likely to be out for 10 weeks and Antolin Alcaraz (groin) ruled out until the New Year.
Ivan Ramis and Gary Caldwell are both doubts for Saturday’s game, so Wigan’s three-man backline could feature midfielder David Jones again.
Arsene Wenger, meanwhile, has no fresh injury concerns after Monday’s win against Reading.
Olivier Giroud (back) could push for a start after his cameo appearance in the 5-2 win, but that position could be reserved for contract rebel Theo Walcott who impressed at the Madjeski.
Andre Santos (stomach) is still struggling, while Abou Diaby (thigh) has been ruled out until after Christmas.
- The Latics have let in at least two goals in their last seven Premier League matches.
- Martinez’s side have won only two of their last 18 Premier League games played in the month of December
- Arsenal have scored at least two goals in their last four away matches against Wigan in all competitions.
- The Gunners have only won twice in their last seven games in all competitions.